Solubility enhancement of nimodipine using mixed hydrotropic solid dispersion technique
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چکیده
منابع مشابه
Evaluation of Enhancement of Solubility of Paracetamol by Solid Dispersion Technique Using Different Polymers Concentration
Paracetamol (PCM) is a non-steroidal anti-inflammatory drug (NSAID), sparingly soluble and bitter in taste. It is widely used as an analgesic and antipyretic. Solid dispersion of drug with different polymers was attempted to improve solubility of paracetamol.The aim of this study was to prepare, characterize and compare solid dispersions of poorly water soluble non-steroidal anti-inflammatory d...
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The aim of the present study was to improve solubility and dissolution of the poorly aqueous soluble drug, etoricoxib by solvent evaporation technique using various sugar carriers, such as lactose, sucrose, and mannitol. Etoricoxib solid dispersions and their respective physical mixtures using lactose, sucrose, and mannitol were prepared in different ratios by solvent evaporation technique. The...
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Solubilization of poorly water-soluble drugs has been a very important issue in screening studies of new chemical entities as well as formulation research. Various techniques are employed to enhance the aqueous solubility of poorly water-soluble drugs and hydrotropic solubilisation is one of them. A hydrotrope is a compound that solubilises hydrophobic compounds in aqueous solution. The problem...
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ژورنال
عنوان ژورنال: Zanco Journal of Medical Sciences
سال: 2020
ISSN: 1995-5588,1995-5596
DOI: 10.15218/zjms.2020.046